IsoTherapeutics Group, LLC

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Welcome to IsoTherapeutics Group!

Company Profile

We develop novel diagnostic and therapeutic agents directed at debilitating diseases by developing our own technologies, and partnering with other companies to help them develop pharmaceuticals. Our extensive in-house facilities allow us to offer unprecedented turn-around times for your project.

Our specialty is therapeutic radiopharmaceuticals.

News at IsoTherapeutics

Latest Publication

Novemger 5, 2011

Bioconjugate Chemistry today published "Comparison of Pretargeted and Conventional CC49 Radioimmunotherapy Using ¹⁴⁹Pm, ¹⁶⁶Ho, and ¹⁷⁷Lu."

Testimonials

"This is the first company I will call whenever I need help with developing radiopharmaceuticals."

David W. Mueller, Ph.D.
CEO, Clear Vascular, Inc.

"This company treats customers as partners and truly provides the best value for your R&D dollars. Check them out whenever you need help with radiochemistry."

Stan Stearns
President & Founder
Valco Instruments Co. and
The Gabriel Institute

"A small company with high caliber people. This company helped me to address critical questions posed by FDA."

Ebrahim S. Delpassand, M.D.
Chairman & Medical Director
Excel Diagnostics

Success Stories

Open Communication and organized learning solved a customer's problem

Problem: While working in close concert with a customer to develop a radiolabeled protein for diagnosing vulnerable plaque, a major problem arose in the midst of the project when the customer lost the ability to process their isotope. Without an alternate source of supply of isotope there was a strong probability that the product development and subsequent path to clinical trial may have to be delayed.

Expertise is Our Strength

IsoTherapeutics has set up a series of competencies for the purpose of aiding our customers/collaborators in the development of pharmaceuticals. The scientific staff at IsoTherapeutics has extensive experience in the development of radiopharmaceuticals, particularly bone-seeking radiopharmaceuticals. Additionally, we have experience designing antibody conjugates for radioimmunotherapy.

Our model is to house the necessary capabilities under one roof to shorten the development time for drug candidates. Capabilities include:

synthetic organic and chelation chemistry, with particular expertise in bifunctional chelants for radiolabeling proteins.
radioanalytical and radiochemistry, with expertise in diagnostic and therapeutic isotopes.
Small animal testing capabilities include the ability to perform biodistribution and pharmacokinetic studies on normal and tumor xenograft models using radiolabeled compounds.
GLP Studies
cGMP manufacturing

Last Update 21 May 2012